Quinolines and derivatives
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Filtered Search Results
Ambeed 3 4Chlorophenyl N pyridin4ylme
3-(4-Chlorophenyl)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide, 915385-81-8, 98%
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Ambeed 1Methyl4piperidinemethanol
1-Methyl-4-piperidinemethanol, 20691-89-8, 97%
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Ambeed 2 2 Bis diphenylphosphino 1 1
2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl, 98327-87-8, 97%
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Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | 98.5% | 482.57 g/mol | C20H42N4O9 | 50 MG
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Azido-PEG9-amine is a non-cleavable nine-unit polyethylene glycol (PEG) linker bearing an azide and a terminal amine. It is used for antibody-drug conjugate and PROTAC synthesis and enables bioconjugation via click chemistry (CuAAC and SPAAC).
- Molecular formula: C20H42N4O9.
- Molecular weight: 482.57 g/mol.
- Cas number: 1207714-69-9.
- Purity: 98.52%.
- Available package sizes: 50 mg, 100 mg, 250 mg, 500 mg, 1 g.
- Storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Compatible with copper-catalyzed azide-alkyne cycloaddition and strain-promoted alkyne-azide cycloaddition for bioconjugation.
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Medchemexpress LLC Mal-amido-(CH2COOH)2 | 207613-14-7 | 99.2% | 284.22 g·mol-1 | C11H12N2O7 | 50 MG
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Mal-amido-(CH2COOH)2 is a maleimidoethyl-containing intermediate used in the synthesis of hydrophilic antibody-drug conjugate (ADC) linkers for research applications. It is supplied as a solid with high purity and is formulated to dissolve in DMSO for downstream conjugation workflows.
- CAS number 207613-14-7.
- Purity 99.2%.
- Molecular formula C11H12N2O7.
- Molecular weight 284.22 g·mol-1.
- Appearance solid; soluble in DMSO with ultrasonic warming and heating to 60°C.
- Storage powder -20°C up to 3 years; in solvent -80°C for 6 months, -20°C for 1 month.
- Intended for research use only; not for human use.
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Medchemexpress LLC B-AP15 | 1009817-63-3 | 98.1% | 419.39 | 200 MG
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B-AP15 is a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14. It is for research use only.
- Inhibits UCHL5 and Usp14 deubiquitinating enzymes
- Induces tumor cell apoptosis
- Available as a solid, light yellow to yellow appearance
- Formula: C22H17N3O6
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AdipoGen Dihydroethidium
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Chemical. CAS 104821-25-2. Formula C21H21N3. MW 315.41. Synthetic. Redox indicator. Blue fluorescence until oxidized to ethidium. Can be used for detecting superoxide radical in cells, tissues and organisms.
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Ambeed 3Aminopiperidine2 6dione
3-Aminopiperidine-2,6-dione, 2353-44-8, 98%
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Apexbio Technology LLC Cyclosporin A 59865-13-3 200mg
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Cyclosporin A is an immunosuppressive agent acting primarily through inhibition of cyclophilins intracellular peptidyl-prolyl isomerases with a reported IC50 of 7 nM Cyclophilins regulate mitochondrial permeability transition pore (MPTP) opening intracellular calcium signaling and NFAT transcriptional activation pathways Cyclosporin A s ability to inhibit calcineurin-NFAT signaling in T-cell activation leads to suppression of inflammatory immune responses indicating potential use in autoimmune disorder research Additionally it modulates cell apoptosis and survival mechanisms in diverse models including retinal ischemic injury viral entry (HBV HCV) and tumor biology in colon cancer cell lines
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Medchemexpress LLC Amino-PEG5-amine | 72236-26-1 | 97.0% | 5 G
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Amino-PEG5-amine is a PEG-based (5 units) PROTAC linker, appearing as a colorless to light yellow liquid. With a molecular weight of 280.36 and a formula of C12H28N2O5, it is soluble in water (≥ 100 mg/mL). This compound is suitable for research use only.
- Used in the synthesis of PROTACs
- Appears as a colorless to light yellow liquid
- Soluble in water (≥ 100 mg/mL)
- For research use only
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Medchemexpress LLC Afalanine (N-Acetyl-DL-phenylalanine) | 2901-75-9 | 99.9% | 200 MG
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Afalanine (N-Acetyl-DL-phenylalanine) is an endogenous metabolite of an endophytic fungus with antidepressant activity. It can be used in combination with antibiotics to prevent renal damage.
- Endogenous metabolite of an endophytic fungus
- Antidepressant activity
- Can be used in combination with antibiotics to prevent renal damage
- For research use only
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Medchemexpress LLC PVD-06 | 3032975-48-4 | 98.3% | 1074.13 | 1 MG
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PVD-06 is a selective PROTAC PTPN2 degrader with a DC50 of 217 nM. It induces PTPN2 degradation via a VHL-, ubiquitin, and proteasome-dependent pathway. PVD-06 can promote T cell activation and amplify IFN-γ-mediated anticancer activity, making it suitable for investigating PTPN2 in diseases such as leukemia and melanoma.
- Selective PROTAC PTPN2 degrader
- Induces PTPN2 degradation via VHL-, ubiquitin, and proteasome-dependent pathway
- Promotes T cell activation
- Amplifies IFN-γ-mediated anticancer activity
- Composed of a PTPN2 ligand, a linker, and a VHL ligand
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Medchemexpress LLC Quin-C7 | 871100-12-8 | MFCD34182190 | 99.8% | 431.48 g/mol | C25H25N3O4 | 10 MG
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Quin-C7 is an orally active antagonist of formyl peptide receptor 2 (FPR2/ALX) used as a research reagent to study inflammatory signaling pathways. It exhibits anti-inflammatory activity and has been reported to ameliorate dextran sulfate sodium (DSS)-induced colitis in mouse models.
- Orally active FPR2/ALX antagonist for in vivo and in vitro studies.
- Demonstrated anti-inflammatory effects and efficacy in DSS-induced colitis models.
- Chemical formula C25H25N3O4, molecular weight 431.48 g/mol.
- CAS number 871100-12-8.
- High purity (~99.8%) suitable for research applications.
- Available as a 10 MG solid; soluble in DMSO for stock solutions.
- For research use only; not for human or clinical use.
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Boston Bioproducts Inc Ethidium Bromide (10 mg/ml) - 10ml
Ethidium Bromide (10 mg/ml) - 10ml (For Research Use and Further Manufacturing Only)
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378950 FEXAGRATINIB 200MG
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